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The Future of Aging Starts in Your Gut

Trilliome is a Swiss biotechnology company translating breakthrough microbiome science into natural, clinically validated solutions that enhance cognition, balance mood, and extend our healthspan.

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Supported by

Venture Kick Reform Tuple EU Superlab Suisse
Innosuisse Reform Tuple EU

The Silent Crisis Fueling Modern Ailments

Modern life is taking a toll on our internal ecosystem. Stress, processed foods, and environmental factors damage the gut microbiome, leading to a state of imbalance (dysbiosis). This isn't just about digestion; it's a root cause of brain fog, mood swings, and chronic inflammation.

brain
Cognitive Decline & Brain Fog

A struggling gut can't produce the vital compounds your brain needs to thrive. This leads to difficulty concentrating, memory issues, and persistent mental fatigue that holds you back.

head
Mood, Stress & Mental Resilience

Many "feel good" factors important for brain are produced in the gut. When this production is disrupted, it can directly impact mood, resilience, and your ability to manage stress.

inflammation
Systemic Inflammation

An imbalanced microbiome can damage the gut lining. This allows harmful substances to "leak" into the bloodstream, triggering a chronic, low-grade inflammatory response throughout the body.

We Target the Root Cause. The Result is Renewed Vitality.

Selectively Enriches Key Beneficial Species

We’ve developed TRI-01, a precision bioactive derived from unique and sustainably sourced plants. It works by selectively nourishing the key beneficial bacteria in your gut that are essential for a healthy gut-brain connection. The result is a noticeable improvement in how you feel and think.

Boost of your gut-resident, brain-protective, anti-inflammatory bacteria
+45-fold
Short-Chain Fatty Acids, protecting from cognitive decline and inflammation
+150%
Gut-resident probiotic bacteria against "leaky gut"
+250%
Uniform efficacy, high tolerability. Just works across diverse gut microbiomes, and does not induce discomfort (e.g. bloating)
+/+

Meet the Minds Rewiring the Future of Aging

Our founders combine deep scientific expertise with global biotech experience to pioneer microbiome-based therapeutics that elevate brain health and extend vitality.

  • Patrick Guye, PhD MBA

    Co-Founder & CEO

    Patrick is a biotech executive and scientist with leadership roles across pharma and startups, including CSO, COO, and Entrepreneur-in-Residence. His work spans inflammatory, metabolic, and age-related diseases, backed by training in synthetic biology and infection biology from MIT and the University of Basel. At Trilliome, he leads company strategy and helps shape scientific direction to advance microbiome-based health solutions.

  • Tim Mak, PhD MBA

    Co-Founder & CBO

    Tim is a scientist and strategist with experience across microbiome research, pharma, and consumer health at Johnson & Johnson and dsm-firmenich. He trained at the Max Planck Institute and University of Cambridge, and brings deep expertise in translating science into global impact. At Trilliome, he leads commercial strategy and co-leads scientific direction to drive innovation in healthy aging.

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