# Trilliome

> Swiss healthcare company developing precision bioactives — plant-derived actives that steer the gut microbiome with high specificity at milligram doses, for healthy-aging products. B2B model: we supply the ingredient plus the science and regulatory pathway behind the claim.

Key facts:

- Based in Switzerland; a platform company — "a platform, not a single ingredient"
- Two ingredients heading to market: TRI-01 (keystone gut bacteria activator) and TRI-04 (precision prebiotic fibre)
- The Teroka platform is a closed loop between wetlab data generation and computational exploration

## Platform & Ingredients

- [The platform (Teroka)](https://trilliome.com/platform): Closed loop between wetlab data generation and computational exploration that steers the gut microbiome with high specificity
- [Ingredients overview](https://trilliome.com/ingredients): TRI-01, TRI-04, and the pipeline behind them — all from one engine
- [TRI-01 — keystone gut bacteria activator](https://trilliome.com/ingredients/tri-01): Shelf-stable, plant-derived active that induces a named four-species consortium of keystone gut bacteria at a low milligram-scale daily dose
- [TRI-04 — precision prebiotic fibre](https://trilliome.com/ingredients/tri-04): Low-molecular-weight, water-soluble prebiotic fibre supporting the gut's butyrate-producing bacteria; Self-Affirmed GRAS pathway
- [Pipeline](https://trilliome.com/ingredients/pipeline): Precision bioactives in development across nutraceutical and cosmeceutical applications


## Science

- [How it works](https://trilliome.com/science): The gut species most linked to brain and metabolic health can't survive a supplement — so Trilliome induces the ones already present in the gut
- [The evidence](https://trilliome.com/science/evidence): In ex-vivo human gut models, TRI-01 induces its four target keystone species, the lead one by up to +45-fold
- [Quality & manufacturing](https://trilliome.com/science/quality): How actives are made, specified and cleared — designed to pass formulation and regulatory due diligence


## Company

- [Company](https://trilliome.com/company): Swiss healthcare company turning the biology of healthy aging into B2B precision bioactives — a platform, not a single ingredient
- [IP & defensibility](https://trilliome.com/ip): Four-layer moat: patents with a favourable patent-office opinion, trade-secret process, and a dataset that compounds over time
- [For investors](https://trilliome.com/investors): A platform, not a product: the engine is the asset, the ingredients are the proof, and the moat compounds; investor updates on request
- [For partners](https://trilliome.com/partners): Precision bioactives plus the science and regulatory pathway behind healthy-aging claims your brand can stand behind


## Legal

- [Privacy notice](https://trilliome.com/privacy): What the website processes, why, who receives it and how long it is kept (nFADP / GDPR)
- [Imprint](https://trilliome.com/imprint): Company details and legal information


## Insights (research notes)

- [The brain is not sealed](https://trilliome.com/insights/the-brain-is-not-sealed.md): The immune cells defending your brain were supposed to last a lifetime. New human data shows they start being replaced around fifty, and the replacements are educated somewhere… — 7 min read
- [A remote control for memory, hidden in the gut](https://trilliome.com/insights/a-remote-control-for-memory-hidden-in-the-gut.md): A new Nature paper shows an aging gut can drive memory loss on its own — and reverse it. The twist is which molecule does the damage. — 4 min read
- [A GLP-1 drug treated depression without touching its receptor](https://trilliome.com/insights/a-glp-1-drug-treated-depression-without-touching-its-receptor.md): A GLP-1 drug relieved depression in mice with its receptor deleted. The effect ran through a single gut bacterium, not the brain. What the science says about the gut microbiome… — 5 min read
- [Beyond biotics: the case for precision bioactives](https://trilliome.com/insights/beyond-biotics-the-case-for-precision-bioactives.md): Probiotics add live bacteria; fibre feeds them in bulk. Our co-founder Tim Mak told Fi Global about a third path — plant-derived bioactives that reprogramme the gut bacteria a… — 2 min read
- [The window for fixing the gut-brain axis closes earlier than we thought](https://trilliome.com/insights/the-window-for-fixing-the-gut-brain-axis-closes-earlier-than-we-thought.md): A systematic review of fifteen trials points to a mid-life prevention window for gut-brain interventions — and it appears to close before clinical disease begins. — 4 min read
- [Diversity is key to a healthy gut](https://trilliome.com/insights/diversity-is-the-key-to-a-healthy-gut.md): Nutrition & Longevity: Walking through Hong Kong's markets — greens, reds, purples, and yellows — highlights a vital truth: diversity in diet is essential for a healthy gut and… — 3 min read
- [Biotech: Building a Commercial Culture](https://trilliome.com/insights/biotech-building-a-commercial-culture.md): Embrace commercial innovation early, even if it requires leadership changes — key insights from Ed Salzman's presentation at the Swiss HLG annual meeting. — 1 min read


## News & company updates

- [Pilot Manufacturing (Sep 2026)](https://trilliome.com/news/pilot-manufacturing)
- [We're in. (Jun 2026)](https://trilliome.com/news/we-re-in)
- [Beyond biotics: the case for precision bioactives (Jun 2026)](/insights/beyond-biotics-the-case-for-precision-bioactives)
- [Trilliome at Vitafoods Europe 2026 (May 2026)](https://trilliome.com/news/trilliome-at-vitafoods-europe-2026)
- [We'll be in Rotterdam, 11–12 May (Apr 2026)](https://trilliome.com/news/we-ll-be-in-rotterdam-11-12-may)
- [Dubai, Microbiome & Longevity (Feb 2026)](https://trilliome.com/news/dubai-microbiome-longevity)
- [1,000 Followers in Under a Year — Thank You for Joining the Trilliome Journey (Feb 2026)](https://trilliome.com/news/1-000-followers-in-under-a-year-thank-you-for-joining-the-trilliome-journey)
- [🚀 Trilliome is heading to Future Food Tech San Francisco (Feb 2026)](https://trilliome.com/news/trilliome-is-heading-to-future-food-tech-san-francisco)
- [Finalists at FI Startup Challenge (Nov 2025)](https://trilliome.com/news/finalists-at-fi-startup-challenge)
- [Biotope Basecamp (Nov 2025)](https://trilliome.com/news/biotope-basecamp)
- [Trilliome Wins 1st Prize in EIT Food's "Food as Medicine" Accelerator and Expands Global Recognition (Oct 2025)](https://trilliome.com/news/trilliome-wins-1st-prize-in-eit-food-s-food-as-medicine-accelerator-and-expands-global-recognition)
- [Vitafood Asia (Sep 2025)](https://trilliome.com/news/vitafood-asia)
- [Startup Pitch Win @ ARDD (Aug 2025)](https://trilliome.com/news/startup-pitch-win-ardd)
- [Trilliome joins Swiss Food & Nutrition Valley (Jun 2025)](https://trilliome.com/news/trilliome-joins-swiss-food-nutrition-valley)
- [Panel Discussion at Association of the European Self-Care Industry (Jun 2025)](https://trilliome.com/news/panel-discussion-at-association-of-the-european-self-care-industry)
- [We just won the Probiota Americas Pioneers 2025 Award! (Jun 2025)](https://trilliome.com/news/we-just-won-the-probiota-americas-pioneers-2025-award)
- [Bilbao, EIT FAN & Corporate Matchmaking (Jun 2025)](https://trilliome.com/news/bilbao-eit-fan-corporate-matchmaking)
- [We're part of EIT "Food as Medicine" (May 2025)](https://trilliome.com/news/we-re-part-of-eit-food-as-medicine)
- [🚀 Trilliome is heading to Vitafoods Europe! (May 2025)](https://trilliome.com/news/trilliome-is-heading-to-vitafoods-europe)
- [Tim's featured in Science Genies Podcast (Apr 2025)](https://trilliome.com/news/tim-s-featured-in-science-genies-podcast)
- [Trilliome goes Okinawa (Dec 2024)](https://trilliome.com/news/trilliome-goes-okinawa)
- [Welcome, Barbara! (Dec 2024)](https://trilliome.com/news/welcome-barbara)
- [CFO on board (Nov 2024)](https://trilliome.com/news/cfo-on-board)
- [1st Level Win with Venture Kick (Nov 2024)](https://trilliome.com/news/1st-level-win-with-venture-kick)
- [Innosuisse Coaching Voucher (Oct 2024)](https://trilliome.com/news/innosuisse-coaching-voucher)


## Conferences & events

- [ICOS Innovation Summit (Sep 28–29 · Amsterdam)](https://trilliome.com/conferences/icos-innovation-summit)
- [ARDD 2026 (Oct 1–3 · Boston)](https://trilliome.com/conferences/ardd-2026)
- [Swiss Nordic Bio 2026 (Oct 1 · Zurich)](https://trilliome.com/conferences/swiss-nordic-bio-2026)
- [MISTA demo day (Oct 22 · San Francisco)](https://trilliome.com/conferences/mista-demo-day)


## Optional

- [Contact](https://trilliome.com/contact): Specs, samples & partnerships — contact form
- [Subscribe to updates](https://trilliome.com/subscribe): Email list for research and company news